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Rabbit Anti-IL-4

 
商品编号:
HZ479011
品牌:
金益柏
规格:
CAS:
库存:
10
售价:
¥0.00
购买数量
- +

产品介绍Product Description

规格:

分类:生化检测

储存条件:

用途:elisa

注意事项:仅供科研

Background:    Interleukin4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of natve CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

specificity :    

– Anti-IL-4 is a rabbit polyclonal antibody unconjugated                 

– specific for IL-4 of human,rat,mouse,chicken,goat       

– use for western blotting,elisa,immunoprecipitation and immunohistochemistry

– Protein G affinity chromatography purification, purity :>95%

– Isotype:  IgG

– mol wt:  15kDa 

Application :   

– Western blotting 1:100-500                 

– Immunohistochemistry 1:100-500                  

– ELISA 1:500-1000                   

– Optimal working dilutions must  be determined by the end user.

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

 Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.

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